KINETIC STUDIES AND MICELLAR EFFECT ON THE AMINOLYSIS OF CERTAIN O-ARYL OXIMES

Article abstract of DOI:10.1016/S0040-4020(01)81707-5

Rate constants for the aminolysis of a few O-aryl oximes with several primary alkyl amines, CH3NH2-------C6H12NH2 in 1:1 water-acetonitrile are reported.Reactions of methylamine with substrates possessing poor nucleofugues are very weakly sensitive to base catalysis while reactions of higher amines are not.Slightly higher rate of long chain amine may be considered as a consequence of hydrophobic interaction.Cationic micelles of cetyltrimethyl ammonium bromide enhance the rate.Magnitude of micellar catalysis increases towards higher amines.