COMBINATION OF BORANE-DIMETHYL SULFIDE COMPLEX WITH CATALYTIC SODIUM TETRAHYDROBORATE AS A SELECTIVE REDUCING AGENT FOR α-HYDROXY ESTERS, VERSATILE CHIRAL BUILDING BLOCK FROM (S)-(-)-MALIC ACID

Article abstract of DOI:10.1246/cl.1984.1389

Borane-dimethyl sulfide complex has proven to be an efficient and selective reducing agent in the presence of sodium tetrahydroborate for α-hydroxy esters as exemplified in the reduction of dimethyl (S)-(-)-malate, providing the versatile chiral building block of four-carbon backbone.