Tetrahedron Asymmetry p. 2721 - 2724 (1996)
Update date:2022-08-11
Topics:
Tempkin, Orin
Blacklock, Thomas J.
Burke, J. Andrew
Anastasia, Maria
The nucleophilic ring opening of (R)-β-butyrolactone 2 with 2-thiophenethiolate is the key step in a straightforward stereospecific synthesis of keto sulfone 1, a precursor to carbonic anhydrase inhibitor MK-0507.
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