Tetrahedron Letters p. 9589 - 9592 (1998)
Update date:2022-08-25
Topics:
Goodman, Murray
Zhang, Jinfang
Gantzel, Peter
Benedetti, Ettore
An expedient and highly stereocontrolled route to (R)-α- methyltryptophan and its orthogonally protected analogs has been developed via a four-step conversion from L-alanine in good overall yields. The stereochemistry of the products is confirmed by X-ray diffraction analysis, NMR spectroscopy and optical rotations.
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Doi:10.1021/ja509029h
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(1997)
