Efficient Metal-Free Catalytic Reaction Pathway for Selective Oxidation of Substituted Phenols

Article abstract of DOI:10.1021/acscatal.5b01222

Selective oxidation of substituted phenols to p-benzoquinones is known to be inefficient because of the competing C-O coupling reaction caused by phenoxy radicals. The poor stability of conventional metal-based catalysts represents another bottleneck for industrial application. Here, we describe a metal-free reaction pathway in which onion-like carbon (OLC) as a low-cost catalyst exhibits excellent catalytic activity and stability in the selective oxidation of mono-, di- and trisubstituted phenols to their corresponding p-benzoquinones, even better than the reported metal-based catalysts (e.g., yield, stability) and industrial catalysts for particular substrates. Together with XPS, Raman, DFT calculations, and a series of comparative experiments, we demonstrate that the zigzag configuration as a type of carbon defects may play a crucial role in these reactions by stabilizing the intermediate phenoxy radicals.

Full text of DOI:10.1021/acscatal.5b01222

Letter
pubs.acs.org/acscatalysis
Efficient Metal-Free Catalytic Reaction Pathway for Selective
Oxidation of Substituted Phenols
Yangming Lin,†,‡ Bo Li,† Zhenbao Feng,† Yoong Ahm Kim,§ Morinobu Endo,∥ and Dang Sheng Su*,†,⊥
†Shenyang National Laboratory for Materials Science, Institute of Metal Research, Chinese Academy of Sciences, Shenyang, 110016
People’s Republic of China
‡School of Chemistry and Materials Science, University of Science and Technology of China, Hefei, 230001 People’s Republic of
China
§School of Polymer Science and Engineering, Chonnam National University, 77 Yongbong-ro, Buk-gu Kwangju, 500-757 Republic of
Korea
∥Carbon Institute of Science and Technology, Shinshu University, 4-17-1 Wakasato, Nagano, 380-8553 Japan
⊥Department of Inorganic Chemistry, Fritz Haber Institute of the Max Planck Society, Faradayweg 4-6, Berlin, 14195 Germany
S
* Supporting Information
ABSTRACT: Selective oxidation of substituted phenols to p-
benzoquinones is known to be inefficient because of the
competing C−O coupling reaction caused by phenoxy radicals.
The poor stability of conventional metal-based catalysts
represents another bottleneck for industrial application. Here,
we describe a metal-free reaction pathway in which onion-like
carbon (OLC) as a low-cost catalyst exhibits excellent catalytic
activity and stability in the selective oxidation of mono-, di- and
trisubstituted phenols to their corresponding p-benzoquinones,
even better than the reported metal-based catalysts (e.g., yield,
stability) and industrial catalysts for particular substrates.
Together with XPS, Raman, DFT calculations, and a series of comparative experiments, we demonstrate that the zigzag
configuration as a type of carbon defects may play a crucial role in these reactions by stabilizing the intermediate phenoxy
radicals.
KEYWORDS: onion-like carbon, molecular model catalysts, phenol, selective oxidation, metal-free
cumbersome preparation processes, inactivation and structure
shrinkage of the catalysts, high toxicity of the catalysts, and
required strongly acidic/highly corrosive conditions. Develop-
ment a new catalytic system with high efficiency and a smaller
environmental footprint for the production of various p-
benzoquinones is therefore demanded.
Metal-free nanocarbon materials have been shown to be
alternative candidates to conventional metal-based catalysts for
some important reactions.30−34 Onion-like carbon (OLC)
obtained by a high-temperature thermal treatment (1500−
1800 °C; see Figure S8 of the Supporting Information) of
nanodiamond in a graphite furnace exhibits a quasi-spherical
morphology consisting of multiple closed concentric fullerene-
like shells and possesses some unique chemical and physical
properties.35,36 OLC have been widely investigated for gas-
phase catalytic reactions, magnetic materials, electrode
materials, and supercapacitors.37−40
atural products with a benzoquinone structure typically
Nplay an important role in biomedicine and the synthesis
of fine chemical compounds.1,2 For example, 2,6-di-tert-butyl-1,
4-benzoquinone (DTBQ) is a highly active antioxidant with
antiaging properties.3 2-Methyl-1,4-naphthoquinone (MNQ,
vitamin K3) is a kind of popular coagulant.4,5 2,3,5-Timethyl-
1,4-benzoquinone (TMBQ) is an important key intermediate
of vitamin E. Traditionally, selective oxidation preparation of p-
benzoquinones from the substituted phenols is known to be
inefficient because of the rather favorable C−O coupling
reaction, as facilitated by phenoxy radicals.6,7 Current studies
have focused on various metal-based catalysts, such as Co(II)−
Schiff base complexes,8 supported heteropolycompounds,9,10
molecular sieves,11−14 heteropoly acids,15 and noble metal
catalysts.16 For the reaction pathways, alternative routes in the
presence of H2O2 or O2 have been developed to improve the
yields of desired products in a homogeneous catalytic
environment. The yields of target p-benzoquinones by these
approaches could reach to ∼55−93%.4,17−29 Despite this, the
drawbacks of these methods involve low selectivity of the
desired p-benzoquinones, the overproduction of byproducts
(e.g. dimeric or polymeric C−O coupling products),
Received: June 11, 2015
Revised: September 2, 2015
© XXXX American Chemical Society
5921
DOI: 10.1021/acscatal.5b01222
ACS Catal. 2015, 5, 5921−5926

ACS Catalysis
Letter
a
Table 1. Catalytic Oxidation of 2,3,6-Trimethylphenol (TMP) over Various Samples under Different Conditions
sel. (%)
yield (%)
entry
catalyst
OLC-1
SBET (m2 g−1
)
T (°C)
conv. (%)
TMBQ
HMPQ
PPO
TMBQ
b
1
80
80
80
80
80
80
80
80
80
80
80
80
60
60
80
80
80
60−70
80
16.5
99.8
91.6
88.6
60.1
52.4
30.3
65.5
40.1
81.4
44.8
97.3
97
13.9
82.5
72.1
72.3
45.5
30.4
24.9
13.4
32.3
58.9
13.5
42.5
87
3.1
15.7
25.2
25.8
52.2
66.7
73.2
84.3
61.6
39.2
81.7
55.4
81.1
2.3
82.3
66.1
64.1
27.4
15.9
7.5
2
3
4
5
6
7
8
9
463
476
trace
trace
trace
trace
trace
trace
trace
trace
trace
trace
trace
OLC-2
OLC-3
OLC-4
AC
459
430
1178
graphite
UDD
305
35
8.8
HHT
13.0
47.9
6.0
c
10
graphene
OLC-1
OLC-1
Ti-HMS
Ti-HMS
Ti−Si
520
463
463
d
11
e
12
41.4
84.3
2
f
13
g
14
3
66.7
100
99
h
15
1288
1288
463
100
90
100
89
i
16
Ti−Si
j
17
OLC-1
40% H2SO4
CuCl2 MgCl2
99.1
>99
>99
76.7
>85
>90
19.7
trace
76.0
>85
>90
k
18
l
19
a
Reaction conditions: 8 mg of catalyst, 0.1 mmol of substrate, 0.36 mmol of tert-butyl hydroperoxide (TBHP), 5 mL of TFT solvent, t = 12 h.
b
c
d
Conducted in the absence of catalyst. Obtained from ref 42, the SBET was recorded on the Micromeritics ASAP2020 analyzer. The reaction
e
conditions are the same as in footnote a, except the oxidant is 30% H2O2. The reaction conditions are the same as in footnote a, except the oxidant
is cumyl hydroperoxide. Reference16, 200 mg of catalyst, t = 240 min, n(H2O2)/n(phenol) = 1, MeOH as solvent. The reaction conditions are the
same as in footnote f, except the oxidant is TBHP. Reference 11, 20 mg of catalyst, t = 40 min, 0.1 mmol of substrate, 0.44 mmol of H2O2, 1 mL of
CH3CN solvent. The seventh cycle test of catalyst under the footnote h conditions. 7 g of catalyst, 12 g of substrate, 3.6 equiv of TBHP, 200 mL of
f
g
h
i
j
k
l
TFT solvent, t = 12 h. MnO2 as oxidant. O2 as oxidant. Desired product: 2,3,5-timethyl-1,4-benzoquinone (TMBQ). Byproducts: 2,2,3,3,5,5-
hexamethyl-4,4-diphenoquinone (HMPQ), polyphenylene oxide (PPO).
In the present study, we demonstrate the excellent catalytic
acitivity of OLC for selective oxidation of representative
substituted phenols (seven examples) to their corresponding p-
benzoquinones. To the best of our knowledge, it is the first
time that the substitute phenol has been catalyzed by metal-free
nanocarbons with decent activity. From XPS, Raman, and other
comparative experiments, we show that the zigzag configuration
rather than the oxygen species is responsible for the enhanced
activities for these catalytic reactions.
Figure S9A−D shows the structures of various OLC samples
consisting of multilayer sp2 fullerene-like shells. The identified
interlayer spacing of ∼0.340 nm in the shell of OLC is assigned
to the (002) of turbostratic carbon graphite.41 The particle sizes
of all OLC samples are ∼5−8 nm, and some lattice disorder can
be observed on the OLC samples (Figure S9, marked by red
arrows). Regarding the N2 physisorption results, there is only a
small difference in the surface area of the OLC samples (Figure
S10 and Table 1).
Table 1 displays the catalytic performances of various carbon
materials for the selective oxidation of 2,3,6-trimethylphenol
(TMP) to 2,3,5-trimethyl-1,4-benzoquinone (TMBQ) under
different conditions. Without catalysts, only 2.3% of TMBQ
yield was obtained (Table1, entry 1) and the main byproduct
was polyphenylene oxide (PPO). The TMP conversion and the
selectivity of the desired TMBQ over the four kinds of OLC
samples were at reasonably high levels (Table1, entries 2−5).
Among the four OLC samples treated at different temperatures,
OLC-1 (treated at 1500 °C) exhibited the best catalytic
performance, with a TMBQ yield of 82.3% under the optimized
reaction conditions (entry 2). In contrast, some other carbon
materials, such as activated carbon (AC, entry 6), graphite
(entry 7), UDD (entry 8), HHT (a commercial high-
temperature-treated nanocarbon fiber with well graphitized
structure; entry 9 Figure S11;), and graphene (G250, entry
10),42 showed a lower yield of TMBQ (∼7.5−47.9%) under
the same reaction conditions. In addition, the dependences of
catalytic performance on time, the amount of TBHP,
temperature, the solvent type, and the oxidant were studied
in detail, and the results are listed in Figure S12 and Table 1,
entries 11−12. Long reaction times; elevated reaction temper-
atures; and increased amounts of TBHP and other oxidants,
including cumyl hydroperoxide and hydrogen peroxide, were
not favorable for improving the selectivity of TMBQ over
OLC-1.
As shown in Figure 1A, the conversion of TMP over OLC-1
is 99.2% along with a TMBQ selectivity of 81.4% after seven
successive runs, indicating that OLC-1 can be repeatedly used.
This catalyst stability was further demonstrated by a low
conversion experiment (the initial conversion of TMP was
maintained at ∼20%, Figure 1B). Although the OLC-1 did not
exhibit better catalytic activity than the reported Ti-HMS and
Ti−Si catalysts using H2O2 as oxidant, it had a remarkable
stability in the selective oxidation of TMP (Table 1, entries 11,
12, 15, 16). Interestingly, the activity of OLC-1 was far more
5922
DOI: 10.1021/acscatal.5b01222
ACS Catal. 2015, 5, 5921−5926

ACS Catalysis
Letter
Table 2. Catalytic Oxidation of Various Substituted Phenols
a
over OLC-1 Catalyst
Figure 1. (A) Recycling test of OLC-1 for selective oxidation of TMP
to TMBQ. Reaction conditions: 8 mg of catalyst, 0.1 mmol of
substrate, 0.36 mmol of TBHP, 5 mL of TFT solvent, T = 80 °C, t =
12 h. (B) Recycling test of OLC-1 for selective oxidation of TMP to
TMBQ. Reaction conditions: 8 mg of catalyst, 0.1 mmol of substrate,
0.36 mmol of TBHP, 5 mL of TFT solvent, T = 40 °C, t = 30 min.
than the Ti-HMS catalyst using TBHP as an oxidant (Table 1,
entry 14). It should be noted that OLC-1 still displayed the
good catalytic performance at preparative production scale
(entry 17). Compared with the conventional homogeneous
industrial catalysts (40% H2SO4 and CuCl2 + MgCl2), OLC-1
not only showed a competing catalytic performance but also
represented a smaller environmental footprint for the
production of TMBQ (Table 1, entries 18, 19).
Following the success of TMP oxidation, we applied OLC-1
to a series of phenols with mono-, di-, and other trisubstituted
structures (Table 2). For all these derivatives, there was a
reasonable conversion and selectivity output. For instance,
TMBQ was produced efficiently from 2,3,5-trimethylphenol
(2,3,5-TMP) and had a conversion of around 100% and
selectivity of 87.5% at 100 °C after 12 hours (Table 2, entry 1).
The selective oxidation for di-substituted phenols, including
2,6-dimethylphenol (DMP), 2,6-dimethylphenol (2,5-DMP)
and 2-methyl-1-naphthol (MNL) resulted in ∼80.9−85.7%
yield of the corresponding p-benzoquinones under the
optimized reaction conditions (Table 2, entries 2, 4, 6 and
Figure S14). Compared with the reported metal-based catalysts
and the industrial homogeneous catalyst (CrO3/CH3COOH/
H2SO4),9,16 OLC-1 exhibited an excellent catalytic performance
in the selective oxidation of DMP, 2,6-di-tert-butyl phenol
(DTBP) and MNL under similar reaction conditions (Table 2,
entries 2, 3, 6). Moreover, a good catalytic performance for the
oxidation of mono-substituted phenol, 2-methylphenol (MP),
can be achieved as expected (Table 2, entry 5). Thus, a cost-
effective metal-free catalytic system to realize the selective
oxidation of phenols has been achieved.
To study the origin of the catalytic performance of OLC,
XPS was employed to investigate the surface composition of
the catalysts. Figure S15A illustrates that with an increase in the
preparation temperature, the full width at half-maximum
(fwhm) value of C 1s spectra decreases from 1.21 eV for
OLC-1 to 1.11 eV for OLC-4. This sugguests that OLC-4 has a
more ordered graphitic structure. As shown in Figure S15B, all
the catalysts have similar oxygen concentrations (0.53−0.64 at.
%). This is also confirmed by elemental analysis (0.33−0.38 wt
%, Table S1). The oxygen peaks located at 530.8 and 533 eV
were assigned to trace CO and C−O (ether group) or C−
OH groups, respectively.35 As reported earlier, oxygen species,
such as a carbonyl group, have been proven to be the active
sites in alkane oxidative dehydrogenation and nitrobenzene
reduction reactions.43,44 In the present work, OLC-4 with C
O group did not exhibit the best catalytic performacne. This
signifies that CO is perhaps not critical to the phenol
oxidation reaction. In addition, the three other catalysts with
a
Reaction condition: 8 mg of OLC-1 catalyst, 0.1 mmol of substrate,
b
0.36 mmol of TBHP, 5 mL of TFT solvent, T = 80 °C, t = 4 h. T =
100 °C, t = 14 h. t = 5 h. t = 8 h. 0.05 mmol of substrate, T = 70 °C,
t = 12 h. Reference 9, 1 mmol of substrate, 5 mLof acetone, 0.02
mmol of Cs3H1M11PV1 heterogeneous catalyst, 22 mmol H2O2, T =
c
d
e
f
g
20 °C, t = 7 h. Reference 16, 200 mg of Ti-HMS catalyst, n(H2O2)/
h
n(phenol) = 1, MeOH as solvent, T = 60 °C, t = 24 h. The reaction
conditions are the same as in footnote f, except the oxidant is TBHP.
i
CrO3/ CH3COOH/H2SO4 catalyst, T = 60−90 °C
similar XPS O 1s spectral profiles (only C−O/C−OH group)
showed different activities (Table 1, entries 2−4); hence, there
is no simple correlation between the oxygen species and the
observed catalytic performance. These results indicate that
oxygen species might not be the active sites in the selective
oxidation of the substituted phenols.
The Raman spectra of the OLC samples have three main
features in the 1000−3000 cm−1 region (Figure S16A): D band
(defect-induced mode, ∼1323 cm−1), the G band (1578 cm−1),
and the 2D band (2652−2678 cm−1). Compared with other
OLC samples, the decreasing fwhm of the D band on OLC-4
represented a more ordered carbon network structure (Figure
S16B). In contrast, OLC-1 had a more disordered carbon
structure. The increased intensity, the asymmetric spectral
profile, and the upshift (from 2652 to 2678 cm−1) of the 2D
band of the OLC samples reflected that the carbon structures
consisting of stacked graphene layers were favorable to
formation of an ordered carbon lattice under elevated
temperature.35,36,45 Moreover, Figure S17 illustrates that there
is no obvious change between fresh OLC-1 and used OLC-1,
suggesting the structural stability of OLC-1 catalyst. The ID/IG
ratio was used to depict the number of defects, especially at
graphene edges.46 The linear relationship of the activity with
the ID/IG ratio in Figure 2 reveals that the ratio is proportional
to the mass-normalized activity and the area-normalized activity
5923
DOI: 10.1021/acscatal.5b01222
ACS Catal. 2015, 5, 5921−5926

ACS Catalysis
Letter
Table 3. Catalytic Performance of TMP over Various Model
a
Molecule Catalysts
Figure 2. Dependences of mass-normalized activity (A) and area-
normalized activity (B) on the ID/IG ratio under different reaction
conditions in the selective oxidation of TMP to TMBQ. Condition A:
80 °C, 12 h. Condition B: 70 °C, 12 h. Condition C: 60 °C, 3 h.
under different reaction conditions, that is, the OLC-1 catalyst
with the highest number of defects exhibits the best catalytic
performance. The same linear relationship could be observed in
the selective oxidation of DMP to DMBQ (Figure S18). In
addition, when commercial HHT with a very low ID/IG ratio
(∼0.35) was used in the oxidation reaction of TMP, a low yield
(∼13%) was obtained (Table 1, entry 9). All the results showed
that defects played a key role in these catalytic reactions.
Defects are rich in nanocarbons, and it has been reported
that many reactions are catalyzed by the defects in carbon;31,47
however, an effective method to identity the type of defect and
to give an accurate description of the amounts of each type is
lacking, even for the total number of defects per square (nano)
meter. It is a challenge to identify the actual active sites because
of the diversity of defects and technical limitations. Although
first-principles calculation was used to study the influence of the
doped Stone−Wales defect structure on ORR,48 exploring the
specific structure of active defect sites in a reaction process is
still an arduous task. Here, we applied several small molecules
as model catalysts to simulate the structures of carbon catalysts
and to identify possible active sites.
a
Reaction conditions: 8 mg of model catalyst, 0.1 mmol of substrate,
0.36 mmol of TBHP, 5 mL of TFT solvent, T = 80 °C, 12 h.
b
c
Conducted in the absence of catalyst. 20 mg model catalysts. Desired
As mentioned, the trace CO and C−O group could be
observed in OLC samples. When different loadings of benzyl
ether and anthraquinone with the mimicked CO and C−O
structures were added into the reaction (Table 3, entries 2−4),
it was found that the catalytic activities did not change as
compared with the blank experiment. This again illustrates that
the surface oxygen species is inconsequential to the catalytic
reaction.
product: 2,3,5-timethyl-1,4-benzoquinone (TMBQ).
is consistent with the conversion rate of TMP (16.5%),
indicating the direct effect of TBHP on the TMP conversion. In
contrast, the decomposition rate of TBHP over OLC-1 was
85.2%, suggesting that the fullerene-like shells had an excellent
decomposition ability for TBHP. It has been reported that the
selective oxidation of substituted phenols may involve a
phenoxy radical coupling process.50−52 The hydroxyl radical
derived from the decomposition of TBHP would get close to
the hydroxyl of the substituted phenol to abstract hydrogen
(this is also the reason for a blank experiment with the TMP
conversion of 16.5%),33,53,54 and then the phenoxy radical was
produced along with the release of water.50−52,55 As mentioned
above (Table 1, entry 1), the main product of the TMP
oxidation was PPO (81.1% selectivity) in the absence of
catalyst. This result was ascribed to the C−O coupling of
phenoxy radicals. Thus, avoiding the C−O coupling must be a
key step.
It has been suggested in the literature that the zigzag edge
may be more reactive than the armchair edge due to its unique
electronic structure and unpaired electrons.56,57 It is therefore
reasonable to expect that the phenoxy radical would be more
stable for binding at the zigzag edge than the amchair edge.
To test this hypothesis, DFT calculations were performed to
study the adsorption of the phenoxy radical at the model
We also employed a few model catalysts with specific
armchair and zigzag defect structures to identify the types of
active sites. As shown in Table 3, two kinds of model catalysts
with an armchair structure do not exhibit an enhanced catalytic
performance (entries 5, 6). It is worth noting that with an
increae in the zigzag unit (Table 3, entries 7−9 and Table S2),
anthracene, naphthacene, and pentacene have an increasing
yield in the selective oxidation of TMP (from 2.7% to 8.4%). A
similar activity tendency for the model catalysts was observed in
the selective oxidation of DMP to DMBQ (Figure S19). All the
facts indicated that the zigzag configuration might have a
positive effect on these reactions. In addition, there was no
obvious synergistic effect between the zigzag and oxygen
species (CO, C−O), as well as for armchair structures
because the yields of TMBQ were only 1.7%, 1.8%, and 2.5%
on xanthenes, pentacenequinone, and coronene catalyst
(entries 10−12), respectively.
As shown in Table S3, only 4.5% TBHP (about 0.0162
mmol) decomposed under the blank reaction conditions, which
5924
DOI: 10.1021/acscatal.5b01222
ACS Catal. 2015, 5, 5921−5926

ACS Catalysis
Letter
catalysts, as shown in Table 3. In Figure 3, the adsorption of the
phenoxy radical at the zigzag edge (five benzene rings) is
ACKNOWLEDGMENTS
■
The authors thank Dr. Linhui Yu, Bingsen Zhang, Jia Wang,
Rui Huang, and Kuang-Hsu Wu for their kind help during this
study. The authors acknowledge financial support from MOST
(2011CBA00504); NSFC of China (21133010, 51221264,
21261160487); and the “Strategic Priority Research Program”
of the Chinese Academy of Sciences, Grant No. XDA09030103.
Bo Li is grateful for a financial grant from the Institute of Metal
Research (Y3NBA211A1). The computing time was partly
allocated from ShenYang Branch, Supercomputing Center of
CAS.
Figure 3. Adsorption energies and structures of phenoxy radical
obtained from DFT calculations. (a) Armchair edge (model catalyst 6
in Table 3), (b) zigzag edge (model catalyst 9 in Table 3). The
negative adsorption energy means the adsorption is exothermic. The
structure optimization is carried out at the B3LYP/6-31G* level, and
the energy is further refined at the B3LYP/6-311G* level of theory. All
calculations are performed by using the Gaussian 09 code.49 Color
code: carbon is gray, hydrogen is white, and oxygen is red.
REFERENCES
■
(1) (a) Saladino, R.; Neri, V.; Mincione, E.; Filippone, P. Tetrahedron
2002, 58, 8493−8500. (b) Fishwick, C.W. G.; Jones, D. W. The
Quinonoid Compounds; Patai, S., Ed.; Wiley: Chichester, 1988; Vol. 1,
pp 403−453. (c) Finley, K. T. The Quinonoid Compounds; Patai, S.,
Ed.; Wiley: Chichester, 1988; Vol. 1; pp 537 − 717. (d) Mariarty, R.
M.; Prakash, O. M. Organic Reactions; Wiley, Hoboken, 2004, 327 −
415.
(2) Takaki, K.; Shimasaki, Y.; Shishido, T.; Takehira, K. Bull. Chem.
Soc. Jpn. 2002, 75, 311−317.
(3) Mohapatra, S. K.; Hussain, F.; Selvam, P. Catal. Commun. 2003,
4, 57−62.
exothermic by 0.23 eV, and it becomes endothermic by 0.85 eV
when the adsorption occurs at an armchair edge. The
calculations clearly indicate that the zigzag edge plays an
important role in stabilizing the phenoxy radical and, hence,
restraining the coupling reaction of C−O on phenoxy radicals.
Subsequently, it could be that a bound phenoxyl continues to
react with the TBHP to afford the corresponding hydro-
quinone, which would then be readily oxidized by TBHP and
finally achieve a high selectivity of the desired p-benzoquinone
products. We believe that a clearer understanding of the
mechanism is still required.
In summary, we have developed a metal-free heterogeneous
catalytic reaction pathway for selective oxidation of substituted
phenols to p-benzoquinones. Onion-like carbon as an efficient
catalyst exhibited high conversion (>99.3%) and selectivity
(∼81.5−92.5%) toward substituted phenols at a mild reaction
condition. It was found that the defects at a zigzag edge played
an important role in these reactions. The catalytic performance
may be attributed to the stabilization of intermediate phenoxy
radicals at the zigzag configuration, as elucidated by the
experimental results and theoretical studies. Our work provides
a new opportunity for the development of metal-free catalysts
and some valuable information for insight into the role of
defects in carbon materials in liquid-phase catalytic reactions.
(4) Bohle, A.; Schubert, A.; Sun, Y.; Thiel, W. R. Adv. Synth. Catal.
2006, 348, 1011−1015.
(5) Sheldon, R. A.; Dakka, J. Catal. Today 1994, 19, 215−245.
(6) Boldron, C.; Aromi, G.; Challa, G.; Gamez, P.; Reedijk, J. Chem.
Commun. 2005, 5808−5810.
(7) Murahashi, S. I.; Naota, T.; Miyaguchi, N.; Noda, S. J. Am. Chem.
Soc. 1996, 118, 2509−2510.
(8) Gupta, K. C.; Sutar, A. K. Coord. Chem. Rev. 2008, 252, 1420−
1450.
(9) Villabrille, P.; Romanelli, G.; Vaz
́
quez, P.; Cac
́
eres, C. Appl.
Catal., A 2004, 270, 101−111.
(10) Villabrille, P.; Romanelli, G.; Vaz
́
quez, P.; Cac
́
eres, C. Appl.
Catal., A 2008, 334, 374−380.
(11) Ivanchikova, I. D.; Kovalev, M. K.; Mel’gunov, M. S.; Shmakov,
A. N.; Kholdeeva, O. A. Catal. Sci. Technol. 2014, 4, 200−207.
(12) Kholdeeva, O. A.; Zalomaeva, O. V.; Shmakov, A. N.; Melgunov,
M. S.; Sorokin, A. B. J. Catal. 2005, 236, 62−68.
(13) Tanev, P. T.; Chibwe, M.; Pinnavaia, T. J. Nature 1994, 368,
321−323.
(14) Kholdeeva, O. A. Catal. Sci. Technol. 2014, 4, 1869−1889.
(15) Ivanchikova, I. D.; Maksimchuk, N. V.; Maksimovskaya, R. I.;
Maksimov, G. M.; Kholdeeva, O. A. ACS Catal. 2014, 4, 2706−2713.
(16) Cheneviere, Y.; Caps, V.; Tuel, A. Appl. Catal., A 2010, 387,
129−134.
(17) Moller, K.; Wienhofer, G.; Schroder, K.; Join, B.; Junge, K.;
̈
̈
̈
Beller, M. Chem. - Eur. J. 2010, 16, 10300−10303.
ASSOCIATED CONTENT
* Supporting Information
The Supporting Information is available free of charge on the
ACS Publications website at DOI: 10.1021/acscatal.5b01222.
■
(18) Wienhofer, G.; Schroder, K.; Moller, K.; Junge, K.; Beller, M.
Adv. Synth. Catal. 2010, 352, 1615−1620.
̈
̈
̈
S
(19) Hay, A. S. U.S. Patent 3,306,874 [P], 1967-2-28.
(20) Rutledge, T. U.S. Patent 3,784,575[P], 1974-1-8.
(21) Costantini, M.; Jouffret, M. U.S. Patent 4,208,339[P], 1980-6-
17.
(22) Michelet, D.; Razoutz, M. U.S. Patent 3,927,045[P], 1975-12-
16.
Materials, additional data and figures about the BET
analysis, elemental analysis, Raman spectra, XPS spectra,
and catalytic reaction conditions for various samples
(PDF)
(23) Braxton, J. H. G.; Closson, R. D. U.S. Patent 3,213,114[P],
1965-10-19.
(24) Reilly, E. L. U.S. Patent 4,257,968[P], 1981-3-24.
(25) Dietl, H. K.; Young, H. S. U.S. Patent 4,360,469[P], 1982-11-23.
(26) Pommer, H.; Schuster, L. U.S. Patent 3,658,852[P], 1972-4-25.
(27) Rappoport, Z.; Yamamura, S. Oxidation of Phenols; Wiley: West
Sussex, U.K, 2003; pp 1153−1346. DOI: 10.1002/0470857277.ch17.
(28) Molander, G. A.; Knochel, P. Comprehensive Organic Synthesis,
2nd ed.; Elsevier: Oxford, 2014, Vol. 3; pp 56−740.
AUTHOR INFORMATION
Corresponding Author
*Phone: +86-24-83970029. Fax: +86-24-83970019. E-mail:
dssu@imr.ac.cn.
■
Notes
The authors declare no competing financial interests.
5925
DOI: 10.1021/acscatal.5b01222
ACS Catal. 2015, 5, 5921−5926

ACS Catalysis
Letter
(29) Allen, S. E.; Walvoord, R. R.; Padilla-Salinas, R.; Kozlowski, M.
C. Chem. Rev. 2013, 113, 6234−6458.
(55) Zombeck, A.; Drago, R. S.; Corden, B. B.; Gaul, J. H. J. Am.
Chem. Soc. 1981, 103, 7580−7585.
(56) Yang, J. H.; Sun, G.; Gao, Y.; Zhao, H.; Tang, P.; Tan, J.; Lu, A.
H.; Ma, D. Energy Environ. Sci. 2013, 6, 793−798.
(57) Enoki, T.; Kobayashi, Y.; Fukui, K. I. Int. Rev. Phys. Chem. 2007,
26, 609−645.
(30) Qi, W.; Su, D. ACS Catal. 2014, 4, 3212−3218.
(31) Su, D. S.; Perathoner, S.; Centi, G. Chem. Rev. 2013, 113, 5782−
5816.
(32) Lin, Y.; Su, D. ACS Nano 2014, 8, 7823−7833.
(33) Li, W.; Gao, Y.; Chen, W.; Tang, P.; Li, W.; Shi, Z.; Su, D. S.;
Wang, J.; Ma, D. ACS Catal. 2014, 4, 1261−1266.
(34) Cao, Y.; Yu, H.; Peng, F.; Wang, H. ACS Catal. 2014, 4, 1617−
1625.
(35) Lin, Y.; Pan, X.; Qi, W.; Zhang, B.; Su, D. S. J. Mater. Chem. A
2014, 2, 12475−12483.
(36) Holec, D.; Hartmann, M. A.; Fischer, F. D.; Rammerstorfer, F.
G.; Mayrhofer, P. H.; Paris, O. Phys. Rev. B: Condens. Matter Mater.
Phys. 2010, 81, 235403.
(37) Keller, N.; Maksimova, N. I.; Roddatis, V. V.; Schur, M.; Mestl,
G.; Butenko, Y. V.; Kuznetsov, V. L.; Schlogl, R. Angew. Chem., Int. Ed.
̈
2002, 41, 1885−1888.
(38) Shenderova, O.; Grishko, V.; Cunningham, G.; Moseenkov, S.;
McGuire, G.; Kuznetsov, V. Diamond Relat. Mater. 2008, 17, 462−466.
(39) Li, S.; Feng, G.; Fulvio, P. F.; Hillesheim, P. C.; Liao, C.; Dai, S.;
Cummings, P. T. J. Phys. Chem. Lett. 2012, 3, 2465−2469.
(40) Pech, D.; Brunet, M.; Durou, H.; Huang, P.; Mochalin, V.;
Gogotsi, Y.; Taberna, P. L.; Simon, P. Nat. Nanotechnol. 2010, 5, 651−
654.
(41) Lin, Y.; Wu, S.; Shi, W.; Zhang, B.; Wang, J.; Kim, Y. A.; Endo,
M.; Su, D. S. Chem. Commun. 2015, 51, 13086−13089.
(42) Chen, C. M.; Zhang, Q.; Zhao, X. C.; Zhang, B.; Kong, Q. Q.;
Yang, M. G.; Yang, Q. H.; Wang, M. Z.; Yang, Y. G.; Schlogl, R.; Su, D.
S. J. Mater. Chem. 2012, 22, 14076−14084.
(43) Wu, S.; Wen, G.; Liu, X.; Zhong, B.; Su, D. S. ChemCatChem
2014, 6, 1558−1561.
(44) Zhang, J.; Liu, X.; Blume, R.; Zhang, A. H.; Schlogl, R.; Su, D. S.
̈
Science 2008, 322, 73.
(45) Bogdanov, K.; Fedorov, A.; Osipov, V.; Enoki, T.; Takai, K.;
Hayashi, T.; Ermakov, V.; Moshkalev, S.; Baranov, A. Carbon 2014, 73,
78−86.
(46) Wang, Y.; Alsmeyer, D. C.; McCreery, R. L. Chem. Mater. 1990,
2, 557−563.
(47) Song, S.; Yang, H.; Rao, R.; Liu, H.; Zhang, A. Catal. Commun.
2010, 11, 783−787.
(48) Chai, G. L.; Hou, Z.; Shu, D. J.; Ikeda, T.; Terakura, K. J. Am.
Chem. Soc. 2014, 136, 13629−13640.
(49) Frisch, M. J.; Trucks, G. W.; Schlegel, H. B.; Scuseria, G. E.;
Robb, M. A.; Cheeseman, J. R.; Scalmani, G.; Barone, V.; Mennucci,
B.; Petersson, G. A.; Nakatsuji, H.; Caricato, M.; Li, X.; Hratchian, H.
P.; Izmaylov, A. F.; Bloino, J.; Zheng, G.; Sonnenberg, J. L.; Hada, M.;
Ehara, M.; Toyota, K.; Fukuda, R.; Hasegawa, J.; Ishida, M.; Nakajima,
T.; Honda, Y.; Kitao, O.; Nakai, H.; Vreven, T.; Montgomery, J. A., Jr.;
Peralta, J. E.; Ogliaro, F.; Bearpark, M. J.; Heyd, J.; Brothers, E. N.;
Kudin, K. N.; Staroverov, V. N.; Kobayashi, R.; Normand, J.;
Raghavachari, K.; Rendell, A. P.; Burant, J. C.; Iyengar, S. S.;
Tomasi, J.; Cossi, M.; Rega, N.; Millam, N. J.; Klene, M.; Knox, J. E.;
Cross, J. B.; Bakken, V.; Adamo, C.; Jaramillo, J.; Gomperts, R.;
Stratmann, R. E.; Yazyev, O.; Austin, A. J.; Cammi, R.; Pomelli, C.;
Ochterski, J. W.; Martin, R. L.; Morokuma, K.; Zakrzewski, V. G.;
Voth, G. A.; Salvador, P.; Dannenberg, J. J.; Dapprich, S.; Daniels, A.
̈
D.; Farkas, O.; Foresman, J. B.; Ortiz, J. V.; Cioslowski, J.; Fox, D. J.
Gaussian 09; Gaussian, Inc.: Wallingford, CT, USA, 2009.
(50) Esguerra, K. V. N; Fall, Y.; Petitjean, L.; Lumb, J. P. J. Am. Chem.
Soc. 2014, 136, 7662−7668.
(51) Kobayashi, S.; Higashimura, H. Prog. Polym. Sci. 2003, 28,
1015−1048.
(52) Lee, Y. E.; Cao, T.; Torruellas, C.; Kozlowski, M. C. J. Am.
Chem. Soc. 2014, 136, 6782−6785.
(53) Li, Y.; Zhang, P.; Wu, M.; Liu, W.; Yi, Z.; Yang, M.; Zhang, J.;
Zhang, G.; Bai, Z. Chem. Eng. J. 2009, 146, 270−274.
(54) Gao, Y.; Hu, G.; Zhong, J.; Shi, Z.; Zhu, Y.; Su, D. S.; Wang, J.;
Bao, X.; Ma, D. Angew. Chem., Int. Ed. 2013, 52, 2109−2113.
5926
DOI: 10.1021/acscatal.5b01222
ACS Catal. 2015, 5, 5921−5926