Synthesis and anti-inflammatory activity of (3,5-di-tert-butyl-4-hydroxybenzylidene) cyclanones and related compounds

Article abstract of DOI:10.1016/0223-5234(91)90152-D

Some (3,5-di-tert-butyl-4-hydroxybenzylidene) cyclanones were synthesized and evaluated for anti-inflammatory activity in carragenin-induced rat paw edema assay. These compounds are slightly less active than phenylbutazone. Their inhibitory effects in vit