RSC Advances
Paper
Acknowledgements
We thank National Natural Foundation of China (No. 21472024
and No. 21242008) for the nancial support.
Notes and references
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Scheme 2 A plausible mechanism of the defluorination and functio-
nization of ethyl 3,3,3-trifluoropropanoylate.
indicating the 3,3-diuoroacrylate was the intermediate.
Although we attempted to isolate the corresponding 3,3-
diuoroacrylamide or monitor other uoro organic compounds
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mechanism (Scheme 2).
2 3
At rst, Cs CO promoted the
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dehydrouorinative elimination of triuoropropanoylate ester
in the presence of one suitable nucleophile, and the resultant
3,3-diuoroacrylate ester was rapidly added by the nucleophile,
then the adduct continued to rapidly undergo elimination to
afford a,b-unsaturated monouorinated carbonyl compound,
and in general, the further addition and dehydrouorinative
elimination continued to occur and nally resulted in the full-
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1
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(
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Conflicts of interest
There are no conicts to declare.
16022 | RSC Adv., 2018, 8, 16019–16023
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