Tetrahedron Letters p. 977 - 980 (1992)
Update date:2022-08-16
Topics:
Alewood, Paul F.
Brinkworth, Ross I.
Dancer, Robert J.
Garnham, Bronwyn
Jones, Alun
Kent, Stephen B. H.
A protocol has been developed for the generation of hydroxyethylamine peptide bond isosteres in a polymer-supported synthesis.This has been used to produce the potent HIV-1 Protease inhibitor JG365 rapidly and in good yield.
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