TSAO derivatives: Highly specific inhibitors of human immunodeficiency virus type-1 (HIV-1) replication

Article abstract of DOI:10.1080/15257779508012432

TSAO derivatives represent a unique class of nucleosides that are specifically targeted at HIV-1 RT. This overview is focussed on the chemical synthesis, the conformational studies, the antiviral and metabolic properties of TSAO derivatives, as well as th

Full text of DOI:10.1080/15257779508012432

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Nucleosides and Nucleotides
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TSAO Derivatives: Highly Specific
Inhibitors of Human Immunodeficiency
Virus Type-1 (HIV-1) Replication
a
a
Maria J. Camarasa , Maria J. Péarez-Péarez , Sonsoles Velázquez
a
a
a
a
,
Ana San-Féalix , Rosa Alvarez , Simon Ingate , Maria Luisa
a
b
c
c
Jimeno , Anna Karlsson , Erik De Clercq & Jan Balzarini
a
Instituto de Quíamica Méadica (C. S. I. C.). Juan de la Cierva , 3.
8006, Madrid, Spain
2
b
Rega Institute for Medical Research, Katholieke Universiteit
Leuven , B-3000, Leuven, Belgium
c
Karolinska Institute, Biochemical Laboratory I , S-10401,
Stockholm, Sweden
Published online: 16 Feb 2007.
To cite this article: Maria J. Camarasa , Maria J. Péarez-Péarez , Sonsoles Velázquez , Ana San-
Féalix , Rosa Alvarez , Simon Ingate , Maria Luisa Jimeno , Anna Karlsson , Erik De Clercq & Jan
Balzarini (1995) TSAO Derivatives: Highly Specific Inhibitors of Human Immunodeficiency Virus Type-1
(HIV-1) Replication, Nucleosides and Nucleotides, 14:3-5, 585-594
To link to this article: http://dx.doi.org/10.1080/15257779508012432
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