A two-step, one-pot procedure using acid chlorides and propargyl amines to form tri-substituted oxazoles via gold-catalyzed cyclization

DOI: 10.1016/j.tetlet.2012.11.013

Source and publish data:

Tetrahedron Letters p. 259 - 261 (2013)

Update date:2022-08-16

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Authors:

Tran-Dubé, Michelle

Johnson, Sarah

McAlpine, Indrawan

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Article abstract of DOI:10.1016/j.tetlet.2012.11.013

2,4-Disubstituted-5-methyl oxazoles were prepared from a 2-step, 1-pot procedure using acid chlorides and propargyl amines. These conditions lead to the formation of propargyl amides in situ followed by AuCl₃ catalyzed cyclization. We were inte

Full text of DOI:10.1016/j.tetlet.2012.11.013

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