1,2 Asymmetric induction in the TiCl4 mediated alkylation of α-methyl-β-silyloxy ketones with Grignard reagents

DOI: 10.1016/S0040-4039(97)00735-1

Source and publish data:

Tetrahedron Letters p. 3785 - 3788 (1997)

Update date:2022-08-25

Topics:

Authors:

Bartoli, Giuseppe

Bosco, Marcella

Sambri, Letizia

Marcantoni, Enrico

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(97)00735-1

Transmetallation of an α-methyl-β-silyloxy ketone with TiCl₄ in toluene affords a cyclic chelation complex which undergoes highly stereoselective alkylation from Grignard reagents at the less hindered side.

Full text of DOI:10.1016/S0040-4039(97)00735-1

Products guided by the article

Product name:(2R*,3R*)-2-methyl-3-phenyl-1,3-butanediol

Cas No:14366-96-2

R&D Labs maybe for 14366-96-2

Xiamen Hisunny Chemical Co.,Ltd

website:http://www.hisunnychem.com

Contact:+86-592-3327115

Address:Unit 603,No.879,Xiahe Road,Meixin Building,Xiamen,China
Sinonine Industry Co.,Ltd

Contact:86+21-56421993

Address:3F,BUILDING 10,NO.2889 JINKE ROAD, SHANGHAI.
Guangzhou Probig Fine Chemical Co., Ltd.

Contact:020-86297874

Address:No.2, 1/F, No.20, Hetai Road,Hebian Village, Baiyun District,Guangzhou,China
Tangshan Moneide Trading Co., Ltd.

Contact:+86-315-8309571

Address:2-7-420 Jidong Building Materials Commercial Center, Tangshan, Hebei, 064000 China
Shanghai Yingrui Biopharma Co., Ltd

Contact:021-3358 8661*8003

Address:shanghai

Relevant to this article

Tetrazoles: A new class of compound for crystallization modification

Doi:10.1039/c0ce00263a
(2010)
Doi:10.1021/ja00723a061
(1970)
Minor and Trace Sterols in Marine Invertebrates. 26. Isolation and Structure Elucidation of Nine New 5α,8α-Epidioxy Sterols from Four Marine Organisms

Doi:10.1021/jo00332a020
(1981)
Doi:10.1246/bcsj.34.1858
(1961)
Doi:10.1002/hlca.19260090133
(1926)
Doi:10.1039/jr9580000789
(1958)

Article Doi