Remarkable Salt Effects in the Highly Enhanced Enantioselective Hydrolysis of Amino Acid Esters with the Active Tripeptide in the Vesicular System

Article abstract of DOI:10.1246/cl.1994.2081

The remarkably high enantioselectivity (k^L_a,obsd/k^D_a,obsd = 67) was attained along with the large rate-enhancement of the L-form substrate for the hydrolytic cleavage of N-dodecanoyl-D(L)-Phe-PNP by controlling the ionic strength ( = 0.03 M, 1 M = 1 mol dm^-3) in the vesicular system.