Tetrahedron Letters p. 6413 - 6414 (1995)
Update date:2022-08-16
Topics:
Klix, Russell C.
Cain, Michael H.
Bhatia, Ashok V.
A convenient synthesis of 5,6-methylenedioxy-1-tetralone (1) is described. The main features of this synthesis are the formation of 6 via a Grignard reaction using succinic anhydride followed by selective reduction and Friedel-Crafts cyclization to generate the desired tetralone 1.
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