Bioorganic and Medicinal Chemistry Letters p. 2193 - 2196 (1996)
Update date:2022-08-17
Topics:
Sinclair, Peter J.
Wong, Frederick
Staruch, Mary Jo
Wiederrecht, Greg
Parsons, William H.
Dumont, Francis
Wyvratt, Matthew
The synthesis of naphthyl- and indolyl-ethers of the immunosuppressive macrolide ascomycin using pentavalent bismuth reagents is described. The in vitro activities of the aryl ether analogs are reported. The indole ether analogs show increased immunosuppr
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