Diastereoselective Addition of Organocuprates on 1,4-Dihydropyridine-3-carboxaldehydes. Synthesis of Chiral 1,4-Dihydropyridyl-3-alcohols and Pyridyl-3-alcohols

DOI: 10.1016/0040-4039(93)85055-2

Source and publish data:

Tetrahedron Letters p. 6399 - 6402 (1993)

Update date:2022-08-29

Topics:

Authors:

Mangeney, Pierre

Gosmini, Romain

Raussou, Sabine

Commercon, Monique

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0040-4039(93)85055-2

Chiral 1,4-dihydropyridyl-3-alcohols are obtained via a diastereoselective (de 90percent->95percent) 1,2 addition of organocuprates on chiral 1,4-dihydropyridine-3-carboxaldehydes and are transformed into chiral pyridyl-3-alcohols (90percent->95percent).

Full text of DOI:10.1016/0040-4039(93)85055-2

Products guided by the article

Product name:3-Pyridinemethanol,alpha,4-dimethyl-,(S)-(9CI)

Cas No:145920-70-3

R&D Labs maybe for 145920-70-3

Onlychem (Jinan)Biotech Co.,Ltd

Contact:86-531-83175885

Address:No. 44, Honglou South Road, Jinan,China
Shanghai Egoal Chemical Co.,Ltd

Contact:+86-21-50333091

Address:Yangming Garden Square 3,YangGao North Road 1188, Pudong New District, Shanghai
Shanghai Massive Chemical Technology Co., Ltd.

website:http://www.massivechem.com/

Contact:+86 21 34943721

Address:Room 435, 4th floor, Building 9, No. 2568 Gudai Road,Minhang District, Shanghai,
NINGXIA DARONG CHEMICALS & METALLURGY CO.,LTD.

Contact:86-952-2179751

Address:Darong Road, Dawukou, Shizuishan, Ningxia 753001, China
Shijiazhuang Yunxuan Im&Export Co.,Ltd.

Contact:+86-311-83037514

Address:No.6 Hongbin Road

Relevant to this article

Copolymerization of carbon dioxide and butadiene via a lactone intermediate

Doi:10.1038/nchem.1882
(2014)
A facile conversion of symmetrical to unsymmetrical thioureas

Doi:10.1016/0040-4039(93)85067-7
(1993)
A Cascade Reaction of Michael Addition and Truce-Smiles Rearrangement to Synthesize Trisubstituted 4-Quinolone Derivatives

Doi:10.1021/acs.joc.0c01662
(2020)
Br?nsted-Acid-Promoted Rh-Catalyzed Asymmetric Hydrogenation of N-Unprotected Indoles: A Cocatalysis of Transition Metal and Anion Binding

Doi:10.1021/acs.orglett.8b00312
(2018)
4-HYDROXY-2-QUINOLONES 19. A NEW SYNTHESIS OF 3-ALKYL-2-OXO-4-HYDROXYQUINOLINES

Doi:10.1007/BF01169841
(1994)
Use of SF₆ for the production of electrophilic ¹⁸F-fluorination reagents

Doi:10.1016/j.jfluchem.2017.10.010
(2017)

Article Doi