The Effect of Solvent on the α-Effect: Abnormal Nucleophilic Reactivity of Substituted Acetophenone Oximate Anions in Aqueous DMSO

Article abstract of DOI:10.1016/0040-4039(95)01426-I

The nucleophilic reactivity of substituted acetophenone oximate anions decreases with increasing base strengthening ability of the substituent, resulting in a positive Hammett ρ value in H2O containing 20 mole percent DMSO.