
Organic Process Research and Development p. 346 - 350 (2010)
Update date:2022-08-28
Topics:
Xue, Xiaowen
Zhao, Xueqing
Li, Fei
Zhuang, Weiping
Lian, Yuanyang
Fan, Jianhui
Fang, Dongsheng
A new synthetic method for nolatrexed dihydrochloride (thymitaq) has been developed. The synthesis was accomplished in three steps featuring the direct conversion of the starting 4-bromo-5-methylisatin into the methyl anthranilate by potassium peroxydisul
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(1971)Doi:10.1016/j.bmc.2018.08.007
(2018)Doi:10.1016/j.bmcl.2004.11.078
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