147149-88-0Relevant articles and documents
A new method for synthesis of nolatrexed dihydrochloride
Xue, Xiaowen,Zhao, Xueqing,Li, Fei,Zhuang, Weiping,Lian, Yuanyang,Fan, Jianhui,Fang, Dongsheng
, p. 346 - 350 (2010)
A new synthetic method for nolatrexed dihydrochloride (thymitaq) has been developed. The synthesis was accomplished in three steps featuring the direct conversion of the starting 4-bromo-5-methylisatin into the methyl anthranilate by potassium peroxydisul