Tetrahedron Letters p. 491 - 494 (1987)
Update date:2022-08-31
Topics:
Mullen, Daniel G.
Barany, George
The synthesis and characterization of a new silicon-containing handle for use in solid-phase synthesis is described.The anchoring linkage derived from this new handle, when treated with fluoride (1.0 equiv.) for 5 min at 25 deg C, releases peptides as their free acids in essentially quantitative yields and without racemization.
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