A one-step synthesis of a deuterated paclitaxel analogue: 10-deacetoxy- (10α-2H)paclitaxel

DOI: 10.1016/S0960-894X(99)00609-5

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 3277 - 3278 (1999)

Update date:2022-08-25

Topics:

Authors:

Dutta, Dinah

Hadd, Harry

Vander Velde, David G.

Georg, Gunda I.

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Article abstract of DOI:10.1016/S0960-894X(99)00609-5

10-Deacetoxy-(10α-²H)paclitaxel was prepared in one step via the samarium diiodide mediated deoxygenation of paclitaxel in the presence of D₂O.

Full text of DOI:10.1016/S0960-894X(99)00609-5

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Product name:10-deacetoxy-paclitaxel

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