2-Isopropylapoisopinocampheylborane, An Improved Reagent for the Asymmetric Hydroboration of Representative Prochiral Alkenes

Article abstract of DOI:10.1016/S0040-4039(00)76949-8

A new hydroborating agent, 2-isopropylapoisopinocampheylborane (ⁱPraBH2, 2f), achieves the asymmetric hydroboration of representative prochiral alkenes in higher optical purities than that achieved by the borane derivatives, 2-organylapoisopinocampheylboranes (R = Me, IpcBH2; R = Et, EapBH2; and R = Ph, PapBH2) previously examined.