IP3 Receptor-Ligand. 1: Synthesis of Adenophostin A

Article abstract of DOI:10.1016/00404-0399(50)0916Z-

Adenophostin A, a potent IP₃ receptor-agonist, was synthesized.The basic skeleton with 3'-O-(α-D-glucosyl)adenosine was constructed by AgClO4-γ-collidine-promoted glycosylation employing 2-O-benzyl-3,4,6-tri-O-acetyl-α-D-glucopyranosyl bromide