Synthesis and anti-arrhythmic activity of aminoguanidine derivatives

DOI: 10.1016/0223-5234(93)90133-Y

Source and publish data:

European Journal of Medicinal Chemistry p. 185 - 193 (1993)

Update date:2022-08-16

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Authors:

Erczi, I

Rabloczky, G

Varro, A

Somogy, G

Kuerthy, M

Body, I Body, I

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Article abstract of DOI:10.1016/0223-5234(93)90133-Y

A series of new aminoguanidine derivatives were synthesized and tested for anti-arrhythmic activity.The compounds selected were investigated on other test models.Finally, compound 13 1-(2,6-dimethylphenyl)-4,4-dimethyl-aminoguanidine-hydrochloride (B-GYKI-38 233) was chosen for detailed study. aminoguanidines / anti-arrhythmic activity

Full text of DOI:10.1016/0223-5234(93)90133-Y

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