Optical resolution of 1-arylethanols with a condensed aromatic ring by lipase from Pseudomonas aeruginosa.

Article abstract of DOI:10.1271/bbb.59.2178

Enantioselective syntheses of both enantiomers of 1-arylethanols with a condensed aromatic ring have been done through acetylation of the racemic alcohols with vinyl acetate in the presence of a lipase from Pseudomonas aeruginosa (Toyobo, LIP). The lipase LIP showed high enantioselectivity and reactivity for the title compounds, reacted acetates, and remaining alcohols were obtained with high optical purity.

Full text of DOI:10.1271/bbb.59.2178

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Bioscience, Biotechnology, and Biochemistry
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Optical Resolution of 1-Arylethanols with
a Condensed Aromatic Ring by Lipase from
Pseudomonas aeruginosa
Katsuya Katoa, Masato Katayamaa, Shozo Fujiia & Hiroshi Kimotoa
a Department of Chemistry, National Industrial Research Institute of Nagoya, Hirate-cho,
Kita-ku, Nagoya 46, Japan
Published online: 12 Jun 2014.
To cite this article: Katsuya Kato, Masato Katayama, Shozo Fujii & Hiroshi Kimoto (1995) Optical Resolution of 1-
Arylethanols with a Condensed Aromatic Ring by Lipase from Pseudomonas aeruginosa, Bioscience, Biotechnology, and
Biochemistry, 59:11, 2178-2180, DOI: 10.1271/bbb.59.2178
To link to this article: http://dx.doi.org/10.1271/bbb.59.2178
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