Natural Product Research p. 1 - 7 (2020)
Update date:2022-08-17
Topics:
Ayub, Anjum
Bano, Zarina
Begum, Sabira
Fayyaz, Shahina
Hassan, Nabila
Iqbal, Erum
Kiran, Zareena
Sara, Sara
Siddiqui, Bina S.
In this study, oleanolic acid and its derivatives were studied for their invivo nematicidal activity against root-knot nematode (RKN) Meloidogyne incognita. A series of C-28-oleanolates including five new (5, 7–10) and seven known (1–4, 6, 11, 12) compounds were synthesised and their nematicidal activity was determined and compared with the standard nematicide furadan for the first time. The structures of the compounds were elucidated through 1H NMR, 13C NMR and EIMS. Compounds 4, 5, 7, 8 and 10 showed ～ 90percent inhibition of RKN at 0.125percent concentration after 72 h showing their potential use in nematicidal control.
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Doi:10.1002/chem.201802419
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