Tetrahedron p. 2551 - 2560 (1994)
Update date:2022-08-16
Topics:
Boogaard, Adrian T.
Pandit, Upendra K
Koomen, Gerrit-Jan
New ellipticine derivatives are synthesized by modification of the cyanogroup of 1-cyano-6-methylellipticine.This resulted in the formation of 1-acetyl- and 1-acetamido-6-methylellipticine.Deprotonation of 1-cyano-6-methylellipticine under the influence of Palladium catalyst leads to a new annelated ellipticine (9).From the derivatives obtained, 9 showed the highest cytostatic activity.
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Doi:10.1016/j.bmcl.2015.09.069
(2015)Doi:10.1016/S0040-4039(99)02294-7
(2000)Doi:10.1002/anie.202107356
(2021)Doi:10.1055/s-1994-35866
(1994)Doi:10.1039/c39940000295
(1994)Doi:10.1080/00397919408011709
(1994)