The utility of the pummerer rearrangement intermediates in the presence of Lewis acids a short and practical synthesis of 4-(2-Di-n-propylaminoethyl)-7-methoxyindole

Article abstract of DOI:10.1080/00397919408011709

The interesting compound 5 was prepared by treatment of 3 with Ra-Ni and LiAlH₄. In turn, 3, was obtained in high yield utilizing the trapping of a Pummerer intermediate, under mild Lewis acid conditions.

Full text of DOI:10.1080/00397919408011709

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Synthetic Communications: An
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The Unility of the Pummerer
Rearrangement Intermediates
in the Presence of Lewis
Acids—A Short and Practical
Synthesis of 4-(2-Di-n-
Propylaminoethyl)-7-
methoxyindole
Christos G. Gourdoupis a & Ioannis K. Stamos b
a University of Patras, School of Health Sciences,
Department of Pharmacy , Rion, Patras, 261 10,
Hellas
b The National Hellenic Research Foundation ,
Institute of Organic and Pharmaceutical Chemistry
and the Center for Molecular Analysis , 48 V.
Konstantinou Ave., Athens, 116 35, Hellas
Published online: 23 Sep 2006.
To cite this article: Christos G. Gourdoupis & Ioannis K. Stamos (1994) The Unility of
the Pummerer Rearrangement Intermediates in the Presence of Lewis Acids—A Short
and Practical Synthesis of 4-(2-Di-n-Propylaminoethyl)-7-methoxyindole, Synthetic
Communications: An International Journal for Rapid Communication of Synthetic
Organic Chemistry, 24:8, 1137-1144, DOI: 10.1080/00397919408011709
To link to this article: http://dx.doi.org/10.1080/00397919408011709

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