Chiral ligands derived from Abrine. 3. Asymmetric Pictet-Spengler reaction of Abrine methyl ester and synthesis of chiral 1,2,3,4-tetrahydro-β-carbolines as promoters in addition of diethylzinc toward aromatic aldehydes

DOI: 10.1016/0040-4039(96)01290-7

Source and publish data:

Tetrahedron Letters p. 5971 - 5974 (1996)

Update date:2022-08-11

Topics:

Authors:

Dai, Wei-Min

Zhu, Hua Jie

Hao, Xiao-Jiang

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Article abstract of DOI:10.1016/0040-4039(96)01290-7

Asymmetric Pictet-Spengler reaction of a number of aldehydes with Abrine methyl ester (1) was performed at room temperature to furnish mainly 3 and high ee was obtained in enantioselective addition of Et₂Zn with PhCHO catalyzed by chiral 1,2,3,

Full text of DOI:10.1016/0040-4039(96)01290-7

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