Journal of the Chemical Society. Chemical communications p. 1793 - 1794 (1994)
Update date:2022-08-30
Topics:
Frejaville, Claudine
Karoui, Hakim
Tuccio, Beatrice
Moigne, Francois le
Culcasi, Marcel
et al.
5-Diethoxyphosphoryl-5-methyl-1-pyrroline N-oxide (DEPMPO), a newly synthesized spin trap, is used for the in vitro spin trapping of hydroxyl and superoxide radicals, and though the spin trapping rates are close to those reported for 5,5-dimethyl-1-pyrroline N-oxide (DMPO), the DEPMPO-superoxide spin adduct is significantly more persistent than its DMPO analogue, a difference which allows the detection of superoxide during the reperfusion of ischaemic isolated rat hearts.
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