Tetrahedron Letters p. 5409 - 5412 (1994)
Update date:2022-08-17
Topics:
Curran, Timothy P.
Pollastri, Michael P.
Abelleira, Susan M.
Messier, Renee J.
McCollum, Theresa A.
Rowe, Campbell G.
Reaction of 3, the N-Boc, O-tosyl derivative of phenylalaninol, with base leads to loss of the Boc and tosyl groups and formation of oxazolidinone 9. Similar reactions have also been examined. A mechanism to explain loss of the Boc group under basic reaction conditions is proposed.
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