Journal of the Chemical Society. Chemical communications p. 2287 - 2288 (1994)
Update date:2022-08-11
Topics:
Fleming
Ghosh
With appropriate protecting group manipulation, the nonactate esters 1 and 3, one from each enantiomeric series, are joined together in an alternating sequence to give the hydroxyacid 7, which is lactonised to give nonactin 8 in 59% overall yield.
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