Highly efficient and stereocontrolled synthetic route to enantiopure ACC derivatives: Synthesis of (+)-N-benzyloxycarbonyl-γ,δ-dehydro-allo-coronamic acid methyl ester

Article abstract of DOI:10.1016/S0040-4039(00)78226-8

Highly diastereoselective cyclopropanation of a chiral α,β-dehydroamino acid derivative, obtained from D-mannitol, leads to a single isomer which has been transformed into the title compound in 65% overall yield. This product can be a useful intermediate