The asymmetric Michael reaction using chiral imines under neutral conditions: Stereochemical evidences in support of a cyclic transition state

Article abstract of DOI:10.1016/0040-4039(94)88365-3

Stereochemical outcome observed in addition [6 + 7], [ent-6 + 15] and [18 + methyl acrylate] have been rationalized by evoking the participation of the corresponding compact approaches 14, 21 and 22.