Synthesis of 1,6-diaminodiamantane

Article abstract of DOI:10.1016/0040-4039(95)01133-3

A new polycyclic diamine, 1,6-diaminodiamantane, was synthesized starting from 1,6-dibromodiamantane. The reaction of 1,6-dibromodiamantane with acetonitrile using H₂SO₄ as catalyst afforded 1,6-diacetamidodiamantane in 72% yield. The reaction of 1,6-diacetamidodiamantane with NaOH afforded 1,6-diaminodiamantane in 50% yield.