A convenient large scale synthesis of O-benzylhydroxylamine

Article abstract of DOI:10.1080/00397919708003349

Synthetically useful O-benzylhydroxylamine can be conveniently prepared in large scale by reaction of N-hydroxyphthalimide and benzyl chloride in phase transfer conditions, followed by acidic hydrolysis of N-benzyloxyphthalimide. The overall yield is over 65%.

Full text of DOI:10.1080/00397919708003349

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Synthetic Communications: An
International Journal for Rapid
Communication of Synthetic
Organic Chemistry
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A Convenient Large
Scale Synthesis of O-
Benzylhydroxylamine
Fabrizio Bonaccorsi a & Raffaello Giorgi a
a Menarini Ricerche S.p.A., Medicinal Chemistry
Department, Via Livornese 897, 56122, S.Piero a
Grado, PI, Italy
Version of record first published: 22 Aug 2006.
To cite this article: Fabrizio Bonaccorsi & Raffaello Giorgi (1997): A Convenient
Large Scale Synthesis of O-Benzylhydroxylamine, Synthetic Communications: An
International Journal for Rapid Communication of Synthetic Organic Chemistry, 27:7,
1143-1147
To link to this article: http://dx.doi.org/10.1080/00397919708003349
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