Base-dependent stereoselectivity in reactions of acyl ligand in phenylacetyliron complex (η5-C5H5)Fe(CO)(PPh3)(COCH2Ph)

Article abstract of DOI:10.1016/S0040-4039(00)91872-0

Alkylation of the anion 4 is only little stereoselective and leads to mixtures of stereoisomeric products 5A,B-9A,B. Proportion of stereoisomers depends strongly on the base employed. Condensation with acetaldehyde or benzeldehyde leads to four stereoisomeric products 11C-F and 12C-F, proportion of which depends also on the bases used. Decomplexation leads in the case of alkylated products to bromides 13, and in the case of aldol product 11 to bromohydrin 14 and epoxides 15 and 16.