Synthesis, solution conformation and biological properties of 2',3'- dideoxy-3'-fluoro-D-erythro-pentofuranosides of 2-thiouracil and 2- thiothymine

Article abstract of DOI:10.1080/15257779508012402

The synthesis of the α- and β-anomers of 2',3'-dideoxy-3'-fluoro-2- thiouridine and 2',3'-dideoxy-3'-fluoro-2 thiothymidine via Lewis acid catalysed nucleoside condensation is described. High resolution ¹H NMR data, solution conformations and b

Full text of DOI:10.1080/15257779508012402

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Nucleosides and Nucleotides
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Synthesis, Solution Conformation
and Biological properties of 2′,3′-
Dideoxy-3′-fluoro-D-erythro-
pentofuranosides of 2-Thiouracil and 2-
Thiothymine
N. E. Poopeiko a , J. Poznanski b , A. Drabikowska b , J. Balzarini c
E. De Clercq c , I. A. Mikhailopulo a , D. Shugar b & T. Kulikowski b
,
a Institute of Bioorganic Chemistry, Academy of Sciences , 220141,
Minsk, Belarus
b Institute of Biochemistry and Biophysics, Polish Academy of
Sciences , 02-106, Warsaw, Poland
c Rega Institute for Medical Research, Katholieke Universiteit
Leuven , B-3000, Leuven, Belgium
Published online: 16 Feb 2007.
To cite this article: N. E. Poopeiko , J. Poznanski , A. Drabikowska , J. Balzarini , E. De Clercq , I.
A. Mikhailopulo , D. Shugar & T. Kulikowski (1995) Synthesis, Solution Conformation and Biological
properties of 2′,3′-Dideoxy-3′-fluoro-D-erythro-pentofuranosides of 2-Thiouracil and 2-Thiothymine,
Nucleosides and Nucleotides, 14:3-5, 435-437
To link to this article: http://dx.doi.org/10.1080/15257779508012402
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