A new nucleophilic ring opening of an activated cyclopropane and a formal synthesis of (+/-)-carbovir.

Article abstract of DOI:10.1271/bbb.59.2091

The reaction of bicyclo[3.1.0]hexane 1, possessing a doubly activated cyclopropane ring, with acetic acid and potassium acetate in DMSO proceeded smoothly to give the adduct 2 in good yield. A formal total synthesis of the potent anti-HIV agent (+/-)-carb

Full text of DOI:10.1271/bbb.59.2091

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A New Nucleophilic Ring Opening of an Activated
Cyclopropane and a Formal Synthesis of (±)-Carbovir
Shinji Tanimoria, Masakazu Tsubotaa, Mingqi Hea & Mitsuru Nakayamaa
a Department of Applied Biochemistry, College of Agriculture, Osaka Prefecture
University, 1–1 Gakuen-cho, Sakai, Osaka 593, Japan
Published online: 12 Jun 2014.
To cite this article: Shinji Tanimori, Masakazu Tsubota, Mingqi He & Mitsuru Nakayama (1995) A New Nucleophilic
Ring Opening of an Activated Cyclopropane and a Formal Synthesis of (±)-Carbovir, Bioscience, Biotechnology, and
Biochemistry, 59:11, 2091-2093, DOI: 10.1271/bbb.59.2091
To link to this article: http://dx.doi.org/10.1271/bbb.59.2091
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