Ribose-modified adenosine analogues as potential partial agonists for the adenosine receptor

Article abstract of DOI:10.1021/jm00020a014

We have adopted a practical three-step route for the synthesis of 2'- and 3'-deoxy analogues of N⁶-substituted adenosines: protection of the hydroxyl groups, replacement of the N⁶-amino by a better leaving group, and combined deprote