Journal of Heterocyclic Chemistry p. 293 - 295 (1999)
Update date:2022-08-11
Topics:
Santana, Lourdes
Teijeira, Marta
Uriarte, Eugenio
(±)-trans-1-[2-(Hydroxymethyl)cyclopentylmethyl]uracil (1) was prepared in two steps and 56% yield from 2-hydroxymethylcyclopentylmethylamine (7) and 3-methoxy-2-propenoylisocyanate (6). Isocyanate 6 was prepared from methyl 3- methoxy-2-propenoate in four steps and 38% overall yield.
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