Journal of Organic Chemistry p. 3518 - 3519 (1994)
Update date:2022-09-26
Topics:
Wipf, Peter
Kim, Yuntae
(+/-)-LL-C10037α and its C(4)-epimer were prepared in nine steps from 2,5-dimethoxyaniline.The concise synthetic route represents the first synthesis of this highly functionalized antitumor antibiotic and is useful for the preparation of analogs of the putative pharmacophore of the Ras farnesyltransferase inhibitor manumycin
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