Synthesis and evaluation of novel dual BRD4/HDAC inhibitors

DOI: 10.1016/j.bmc.2017.04.043

Source and publish data:

Bioorganic and Medicinal Chemistry p. 3677 - 3684 (2017)

Update date:2022-08-11

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Authors:

Amemiya, Seika

Yamaguchi, Takao

Hashimoto, Yuichi

Noguchi-Yachide, Tomomi

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Article abstract of DOI:10.1016/j.bmc.2017.04.043

Epigenetic regulation of gene expression via histone acetylation modulates many cellular processes, including apoptosis, the cell cycle, cell growth and differentiation, and inhibitors are promising drug candidates. We have previously developed inhibitors

Full text of DOI:10.1016/j.bmc.2017.04.043

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