Regioselective thermal cage-opening reactions of 4-amino substituted 1,3-bishomocubanones

Article abstract of DOI:10.1016/S0040-4039(98)02116-9

Thermolysis of 4-substituted 1,3-bishomocubanones is strongly dependent on the electronic nature of the bridgehead substituent. 4-(N-benzyl)amido- substituted cage compounds 12 unexpectedly furnish bicyclic annelated cyclopentenones 13, whereas the 4-acet