The Conformational Equilibrium of Chorismate in Solution: Implications for the Mechanism of the Non-Enzymic and the Enzyme-Catalyzed Rearrangement of Chorismate to Prephenate

Article abstract of DOI:10.1021/ja00250a040

The temperature variation of the 1H NMR coupling constants of chorismic acid and of the bis(tetra-n-butylammonium) salts of chorismate and of 4-O-methylchorismate in water and in methanol has been studied.The results show that 10-40percent of each of thes