A convenient synthesis of benzo[c]phenanthridine alkaloid, chelerythrine, by the palladium-assisted internal biaryl coupling reaction

DOI: 10.1248/cpb.44.1634

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1634 - 1636 (1996)

Update date:2022-08-18

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Authors:

Harayama, Takashi

Akiyama, Toshihiko

Kawano, Kazuko

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Article abstract of DOI:10.1248/cpb.44.1634

Total synthesis of chelerythrine, a benzo[c]phenanthridine alkaloid, was accomplished via the internal aryl-aryl coupling reaction of halo-amide (4) by the palladium-assisted cyclization reaction.

Full text of DOI:10.1248/cpb.44.1634

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