Bioorganic and Medicinal Chemistry p. 1487 - 1492 (1996)
Update date:2022-08-11
Topics:
Ghosh, Soumitra S.
Dakoji, Srikanth
Tanaka, Yasuhiro
Cho, Young J.
Mobashery, Shahriar
Carboxypeptidase A (CPA), and other zinc-dependent proteases, facilitate an α deprotonation of judiciously designed ketones and amides. This adventitious reaction has been used in the development of effective mechanism-based inactivators for this family o
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Doi:10.1039/c5nj03033a
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