
Synthetic Communications p. 1575 - 1587 (1995)
Update date:2022-08-24
Topics:
Kostova
Dimitrov
An improved strategy for synthesis of 1-chloro-bicyclo[2.2.2]octane is described in which the key compounds 1-norbornyl substituted ethyl formate or 1-norbornylcarbaldehyde were prepared from 1-norbornyllithium. The latter appeared as a useful precursor for the synthesis of various organic bridgehead substituted derivatives.
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