Novel and efficient one-pot synthesis of N'-alkyl-N,N-dimethylacetamidines

Article abstract of DOI:10.3184/174751911X556963

An efficient method for the synthesis of N'-alkyl-N,N-dimethylacetamidine derivatives under mild conditions and in excellent yields involved reacting primary alkylamines with N,N-dimethylacetamide in the presence of LiCl as a catalyst and methanol as the acetalising reagent.