Natural Product Chemistry, Part 108. Synthesis of 7,7'-Oxy-dicoumarin, the Potential Precursor of Lasioerin and Gnidicoumarin (Short Communication)

Article abstract of DOI:10.1007/BF00809238

The synthesis of 7,7'-oxy-dicoumarin from 7-hydroxycoumarin and 7-bromocoumarin via Ullmann synthesis is described.In contrast to the literature, from the reaction of m-bromophenol with 2-hydroxy succinic acid, 7-bromocoumarin as well as 5-bromocoumarin were obtained. - Keywords: 7,7'-Oxy-dicoumarin; Ullmann-synthesis; 7- and 5-Bromocoumarin