Tetrahedron Letters p. 3675 - 3678 (1991)
Update date:2022-08-11
Topics:
Amann
Zenk
A highly regio- and stereoselective microsomal-bound cytochrome P-450 NADPH dependent enzyme has been discovered in pig liver which is responsible for the intramolecular phenol oxidative coupling of (R)-reticuline to salutaridine, thus giving rise to the morphine skeleton in mammals.
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